Scientific Data Posters

1. Pro-apoptotic effect of the active metabolite of ANA773, a toll-like receptor 7 agonist, on chronic lymphocytic leukemia cells in vitro; synergism in combination with a NF-kB inhibitor American Assocation for Cancer Research, April 2008
2. Dose schedule modulates the pharmacodynamic response to ANA773, a prodrug of a toll-like receptor (TLR)-7 selective-agonist American Assocation for Cancer Research, April 2008
3. Pathway to Selection of a Potent, Well Tolerated Development Candidate in HCV 21st International Conference on Antiviral Research, April 2008
4. Pyrrolo[1,2-b]pyridazin-2-ones as potent inhibitors of HCV NS5B polymerase Hep DART, December 2007
5. 4-(1,1-Dioxo-1,4-dihydro-1λ⁶-benzo[1,4]thiazin-3 -yl)-5-hydroxy-2H-pyridazin-3-ones as novel inhibitors of the HCV NS5B polymerase Hep DART, December 2007
6. ANA598, a Novel Non-Nucleoside Inhibitor of HCV NS5B Polymerase, Exhibits Favorable Pharmacokinetic Properties in Multiple Preclinical Species American Association for the Study of Liver Diseases, October 2007
7. Preclinical Characterization of a Novel, Potent, and Pharmacokinetically Appealing Non-Nucleoside Inhibitor of HCV NS5B Polymerase 14th International Symposium on Hepatitis C Virus and Related Viruses, September 2007
8. The active metabolite of the TLR7 agonist prodrug ANA773 activates anti-tumor activity by natural killer cells American Assocation for Cancer Research, April 2007
9. The effect of dose schedule on the pharmacodynamic response to ANA773, a prodrug of a toll-like receptor 7 specific-agonist American Assocation for Cancer Research NCI-EORTC, April 2007